Scientists May Have Figured Out Why Young People Are Getting Colorectal Cancer More Often

An overall bacterium in the gutter can increase more than we know. This week a study found an evidence that a mutagen toxin produced by some strains They have exhibited cold Starting colorectal cancer can start early.

Scientists of the University of California led the San Diego research. published Wednesday in nature. Colibactin, called toxins and colorectal cancers found a connection between the exposure to the acquisition of young adults. Findings can explain why early startup color cancer can be a mysteriously rising in the past years of starting cancer in recent years, although researchers say.

Colorectal cancer is the fourth most common cancer with about 150,000 Americans every year. The second most leading cause of death by cancer is killed around 50,000 Americans every year.

As in many types of cancer, the death and death rate of colorectal cancer decreases by time. However, this landing is not equally distributed because the colorectal cancer is growing in young and middle-aged adults. According to the American Cancer Society, colorectal cancer rates among people under 50 increased between 2.4% to 2012 and 2021 per year.

Scientists are not sure why these cancers are more common in small Americans, although some studies point to their finger Exhaust foods, higher obesity rates and other lifestyles factors. But this new job adds another suspect.

Researchers do not look specifically to open this mystery; Some parts of the world were interested in understanding why the higher colorectal cancer rates are higher than others. To do this, they analyzed the genetic signature of colorectal cancers with about 1,000 world. These samples include both late and early starting cancer.

Colibactin is known to cause mutations in our cells that can raise the risk of cancer, and former investigations have linked it to colorectal cancer. However, researchers were surprised that the mutations associated with the coilivact are about three times more in early starting cancers, compared to late start cancer. These coilivactin mutations offer that these cancers play a vital role in the fuel role, the mutations related to these colbactin also found molecular evidence to appear early in the development of a tumor.

Combined with other studies that show that mutations associated with Colivactin are often visible in the first ten years of life, these toxins claim that the start of the starting colorectal cancer can be a key income.

“This mutation samples are a kind of historical record in the genome, and they point to the early-life exposure to Colibactin, which is a driving force behind early starting disease. statement from the university.

Researchers note that Colibactin can still be a large piece of a larger puzzle. It is noted that the mutations of the coilivact in more rural areas of the world are rare. Thus, such as diet or antibiotic use, other environmental factors can be encouraged to grow the production of cylivact E. coli Bacteria in the gut can be other reports that can explain higher cancer rates in various countries, in the United States outside the colibactin.

However, the team’s results provide a fertile place for future research and maybe maybe slow down the increase in early starting cancer interventions. Researchers hope to learn that the probiotics can eliminate this more harmful E. coli They try to develop early detection tests that can display for mutations related to colibactin.

At the same time, it is a condition of financing all this work. Researchers noted that the US government is in President Donald Trump aggressive limited finance From the national health institutions in recent months – the same kind of finance can go on important cancer research.

“If the NIH financing affects our ability to do this, it will be a significant hit in the United States, but also Alexandrov,” Alexandrov said. “He said Alexandrov.” Such a scale of such a scale is what possible discoveries. “