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Some common germs can plant seeds for dementia in life. Today, research found a relationship between several infectious diseases, especially Herpes Simplex-1 (HSV-1) and Alzheimer’s disease risk.
Scientists in Gilead scientists conducted research, published BMJ open on Tuesday. The medical documents of people with Alzheimer’s and related conditions have analyzed their medical records, and the conditions related to this situation were a diagnosis of HSV-1. Findings are the latest to suggest that HSV-1 and similar viruses can be an effective measure of the prevention and treatment of similar viruses.
Is the most common form of Alzheimer’s dementiaToday, about 7 million Americans affect. In most cases, environmental and / or genetic factors cause a complex mixture. In recent years, many studies have proposed to include a certain infection-HSV-1 – this can be part of the equation. HSV-1, a large number of infected people is the main cause of oral herpes, known as cold wounds in several or no symptoms. You can also cause genital herpes (primarily HSV-2 causes).
And from all learn However, this viral link was supported, so the authors decided to look for themselves with the help of real world information. According to Luee Liu, this is the first job to use a large database of insurance requirements in the United States to investigate the connection between Alzheimer’s and HSV-1.
Liu and his team, Alzheimer’s age, sex, sex, sex and other factors, about 400,000 Americans diagnosed with people, compared their health results. The only small part of the people who are diagnosed with Alzheimer’s only a small HSV-1 were (a little 0.5%), but there were still more often (about 80% more).
Researchers then looked at a larger group of people who have other types of dementia related to Alzheimer. They found a contact between Alseimer and the other two Herpesvirus, Herpes Simplex-2 and varicella zoster virus, trade and shingles. It is interesting that they are less developed than people who are not treated by antiviral treatment for HSV-1 and do not treat the infection, but they can compress and shorten the active occurrence).
Such observation research cannot prove a reason and effect link between HSV-1 and Alzheimer’s, but the work for such a connection was just strengthened.
“Herpesviruses are likely to be exposed to Alzheimer’s disease and other dementia and antiherpitic medications can be a protector against Alzheimer’s and related dementia,” A viroologist in Gilead said in a virology of Gilead.
There are also important questions about the association, including the actual mechanisms involved. Some research suggested the immune system of our brains amilloid beta and earn For example, to defend from Herpesvirus infection (the wrong forms of these proteins are the main drivers of Alzheimer’s. However, HSV-1 and similar viruses can be more likely to turn off or accelerate the situation.
Other factors, undoubtedly, many people in the life of many people, the HSV-1 contract, but never plays a role because Alzheimer’s does not develop. Two-thirds of the world’s population under 50 carry According to the World Health Organization HSV-1. Researchers show that the links of the HSV-1 / Alzheimer’s link is even stronger and other studies, APOE-ε4 allele people, a genetic version that increases the risk of Alzheimer’s risk, the HSV-1 infection. Thus, these viruses are probably one of the many dominos that lead to Alzheimer’s.
Again, the general evidence shows that people can reduce the risk of dementia by the treatment or prevention or prevention of certain infections. Found a relationship between several research Reducing vaccination and reduced Alzheimer’sfor example. Can Liu notes that can he lower the risk of antiviral treatment for herpes? Research continues Develop vaccinations HSV-1 and HSV-2 can be more valuable than currently accepted for research.
“These findings pay a bigger attention, despite the prevention of herpesvirus, as a public health priority,” said researchers.
