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Peptide-1 receptor agonists like GucaGon, Aka GLP-1 Agonists like Semaglutide – a better known as ozemptic, not for the management of the type 2 diabetes, but also popular losing weight loss benefits. The increase in popularity is mainly due to the power of popular approval and social media. According to a research letter In August 2024, the number of semaglutide recovery, which was published between December 2021 and December 2023, increased by 442%. Ozemptic Made more than 70% of the fillings.
Type 2 outside the loss of diabetes and weight loss, GLP-1 agbonists can reduce blood pressure, improve lipid diseases, increase inflammation and improve heart health. With such advantages, the demand for GLP-1 agonists continues to grow, and today makes one of the most talking treatment.
What are GLP-1 agonists?
GLP-1 Agonists are also known as the cunning mass, first of all, types of medicines used to deal with type 2 diabetes and in some cases.
“Peptide (GLP-1), like a glucagon, is a hormone naturally occurring in the small intestine that causes the release of insulin in the pancreas. This process helps adjust the level of blood sugar,” Angela Haynes-FerereAssociate Professor in the nurse Emory School in Atlanta. “The GLP-1 Agonist imitates the movement of this natural hormone. After meals, blood sugar will rise, and these drugs cause more insulin to help reduce the blood sugar.”
In addition to control blood sugar to people with type 2 diabetes, this medication reduces the appetite. Slows the digestive process, so patients say they feel full of less food. It results in weight loss for many users, but many different factors vary, said Haynes-Ferere.
According to Cleveland Clinic, most GLP-1 agbonists available Like a liquid medication that should be shown under the skin, except for someone available in the form of a tablet (Rybelseus).
A few General and brand names GLP-1 Agonists, Johns Hopkins according to diabetes according to the sick guide:
- Duelaglutide is sold for the trio
- ExeTreaty is sold as widespread, byduron
- Exenatide, sold as ayet
- Lixisenatide is sold as Adlinxin
- Liraglutide, sold as Victosa
- Semaglutide, ozemptic sold
- Sellutide Oral for sale as Rybelsus
- For Sale as a Tirzepatide, Mounjaro or Zepbound (Double GLP-1 / GIP Agonist)
Each brand has its own recommended dose and intake frequency. Some can be taken once a day, while others are used weekly. You have to consult your doctor to understand the best of dosage and frequency.
Potential GLP-1 Agonist Benefits
“In addition to driving blood sugar and reduce obesity, these drugs are shown to reduce cardiovascular risks and improve the renal function,” Haynes-Ferere. Anecdotally, individuals reported reduced cigarettes, gambling, alcohol acceptance and drug use.
“Studies showed the benefits of heart failure and obstructive sleep apnea in patients with heart failure and obstruction of kidney disease,” says Dr. Leon JononsA specialist and clinical associate professor of the Clinical file of Internal Medicine and Metabolism in Iowa Medical College.
According to Cleveland Clinic, others considerations GLP-1 Agonists may include:
- To reduce blood pressure
- Improving lipid diseases
- Reducing Systematic inflammation
- Delay the course of kidney disease associated with diabetes related to diabetes or diabetes, AKA DKD
These advantages are only effective in GLP-1 agonists that are elegant to manage type 2 diabetes, but also helps better cardiovascular health. However, the influence of GLP-1 agonists varies from one to another. GLP-1 Talk to your doctor to understand how the winner can benefit your unique situation.
GLP-1 Agonist side effects and risk of thinking
Lose weight loss for some patients, especially in patients with less skin elasticity, can cause the undesirable cosmetic effects of a Gaunt face. Added that with weight education can help regularly protect muscle mass and keep a healthy look.
The side effects of drugs are mainly related to nausea, constipation, diarrhea or intestine – mainly with the gastrointestinal system. For most patients, these effects are mild and solved over time. For some, the side effects can be heavy and patients should stop drugs, Jons said.
Others side effects According to the National National Medicine Library, GLP-1 Agonists cover the following:
- The loss of appetite
- Vomiting
- Headache
- Dizziness
- Light tachycardia (heart rate increased)
In some cases, small episodes of hypoglycemia may occur. “Hypoglikemia would be extremely rare and other diabetes that can reduce the most of the blood sugar will take place in patients,” said Dr. Troy Mensen, Chicago and a family medical doctor who is a member of the CNET medical view. Cleveland Clinic, hypoglycemia is a situation where blood glucose levels Below 70 mg / dl. If it is not treated, there may be a life-threatening. The symptoms of hypoglycemia, vibration, weakness, heartbreak, concentrate and dizziness may include difficulty. Can treat sugar or hypoglycemic consuming carbohydrates.
In addition, doctors do not recommend GLP-1 agonists to pregnant people because they can pose a threat to developing fetus. If you are pregnant, please contact your doctor if you are planning to get pregnant or breastfeeding.
Who should the GLP-1 agonist accept?
Doctors first recommend GLP-1 agbonists for 2 types of diabetes and obesity. However, GLP-1 agbonists are not the first choice of first treatment. Metformin, a drug from mouth, remains first choice Type 2 to manage diabetes. However, doctors may recommend GLP-1 agbonists:
- Cannot stand the metform
- They cannot lower blood sugar levels with drugs that continue in three months
- Experience of complications for other conditions such as heart failure, atherosclerosis or chronic kidney disease
Cleveland Clinic, doctors can recommend two GLP-1 agonists, semaglutide and liraglutideFor treatment obesity. Dr. Mensen adds that double GLP-1 / gip agonist, can be recommended.
“Based on this drug, based on the fact that each individual experience is different, the patient should work with the best treatment plan and purpose for general well-being,” Haynes-Ferere.
In addition, GLP-1 agbonists like Dulaglutide, Semaglutide and Liraglutide are shown to ensure the cardiovascular benefits. Doctors can also recommend this GLP-1 agbonist reduce risk of heart disease.
It is recommended frequency In general, the intake for GLP-1 agonists designated:
- Dulaglutide: Weekly
- Exenatide: Twice a day
- ExeTreaty Extended Issue: Weekly
- Liraglutide: Daily
- Semaglutide: Weekly
- Tirzepatide: Weekly
- Semaglutide Tablets: Daily
Who should not get a GLP-1 agonist?
GLP-1 Agonists may not be suitable for anyone, although the Type 2 can help you treat diabetes and obesity effectively. You may have your doctor avoid To set GLP-1 agonists if you have:
- Medullary History of Thyroid Cancer: This is due to the use of rare thyroid cancer GLP-1 agbonists in rodents. Your doctor is afraid to determine GLP-1 agonists if you have a family history of medullary thyroid cancer.
- Multiple Endocrine Neoplazia Syndrome Type 2 or Men2: A rare situation characterized by tumors in the endocrine glands. Doctors can be diagnosed because they can stimulate abnormal cells or prevent family history of family history or a family history.
- Pregnant people: Doctors can not recommend GLP-1 agbonists to pregnant people because they can cause risk for developing fetus.
- History of pancreatitis: Doctors, GLP-1 Agonists, because they can increase the risk of fatal hemorrhagic and necrogagic and necrogagic and necrogagic and necrogagic, avoid the most GLP-1 agonists for people in people with pancreatitis history.
- Inflamed intestinal diseases or gastroparez: GLP-1 Agonists emptied slow stomach and disrupt the symptoms of inflammatory bowel diseases.
GLP-1 Overtos and Important Information To Remember
GLP-1 Agonists are prescription drugs and should only be under control of your doctor. It can help prevent excessive doses after the recommended dose. According to American poison centers, often the excessive dose of GLP-1 cause Simple symptoms include side effects:
- Nausea
- Diarrhea
- Vomiting
- Abdominal pain
- Constipation
However, the term of these symptoms may be longer. In severe cases, you can survive dehydration and hypoglycemia that may require immediate medical care.
You need to double check the dose before taking medication and set a reminder for the next dose to prevent the risk of excessive doses.
When will you contact a doctor
If you experience serious side effects after using a GLP-1 agonist, you need to contact your doctor:
- Nausea
- Abdominal pain
- Dizziness
- Increased heart rate
- Vibrate or vibrate
Also, if you think the drug does not work for you or you do not continue the medicine, consult your doctor first.
In addition, regular planning chase It is important to your doctor when you are in GLP-1. These persecution helps to follow your blood glucose levels and determines if any dose changes are necessary. Regular followers can also help doctors to monitor the symptoms of hypoglicemia, kidney disease, pancreatitis and thyroid cancer.
Bottom line
GLP-1 Agonists are primarily Type 2 diabetes and obesity drugs. However, recent studies can reduce blood pressure, reduce inflammation and improve lipid diseases. There are several brands, each has its own dosage rules. However, GLP-1 agbonists may not be suitable for everyone. You should talk to your doctor to understand your GLP-1 Agonists for your situation.
