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Sperm donor with a rare cancer mutation associated with 10 cancer in children


In Europe, a single donor was reported to be used At least 67 pregnancyThe donor was a mutation that caused rare cancer.

Donor’s mutation, according to the guardian report, has been linked to the diagnosis of cancer in 10 of children.

The case was brought to light after contacting fertility clinics after two families Diagnosis of children’s cancer Related to a rare genetic variant called TP53.

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A mutation in TP53 gene causes Li-Fraumeni syndrome to increase the risk To develop cancer. At the Cleveland Clinic, this disorder comes with a sort of 60 years of age and comes with a 90% chance of 50% chance until the age of 40.

The European Sperm Bank, a supplier of sperm, confirmed that this option was attended by some donor sperm.

Doctor with Sample Cup

Dr. researcher. Edwige Kasper (not described), a lawyer for the European limit for birth or number of families for a donor. (Idle)

Guardian, Rare Option “It was not known to be associated with cancer during the gift in 2008.”

The genetic option will not be detected through a standard examination and the donor is currently in good health.

“The defined mutation is one that cannot be discovered by the methods we use in accordance with the rules.”

Dr Edwige Kasper, a biologist at Rouen University Hospital in France, presented this work in the European Human Genetics Society, said the European limit was needed at the annual conference last week Number of birth or families for a single donor.

“We can’t make a whole genome sequence for all sperm donors – I do not argue for it,” he said. “But this is an abnormal spread of genetic disease. Everyone has 75 children in Europe.”

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Kasper analyzed the mutation in his laboratory, probably caused by cancer, and the children born from this donor “should get genetic advice.”

The research forwarding investigation was followed by 67 children of 46 families in 8 European countries. This Children were testedwith the option of 23 of them.

It was reported that the 10-diagnosed diagnosed, leukemia and non-hodgkin lymphoma cases.

New baby

The sixty-seven children of 46 were identified from a donor in 8 European countries. (Idle)

In a statement sent to the digital fox, the European Serman Bank said that the reproduction of reproduction “generally a significantly secure alternative” without reproduction without reproduction with reproduction genetic examination.

The Bank added that the dedicated medical examination of sperm donors, a “broader health examination” with a “wide” test for the history of the donor’s family and genetics “Wide Health Examination” Infectious diseases.

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“However, it is impossible to rule out all the risks – and in this case, the defined mutation could not be discovered by the methods we use in accordance with the rules and demanded a specialized genetic test.

Julie Paulli Budtz, VP. Corporate communication in the European SPERM Bank, Fox News is digital, “This work is deeply affected.”

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“Donor was thoroughly tested outside the necessary standards, but the preventive genetic choices reach the restrictions here,” he said.

“Each person has about 20,000 gene and if you do not know what you are looking for, it is simply simply simply not possible to detect the disease in a man’s gene pool.”

Eggs and sperm in liquid nitrogen tank

Eggs and sperm are kept in the liquid nitrogen tank in the fertility center in Berlin. (Photo Alliance via Jens Kalaene / Getty Images)

Budtz noted that the European SPERM bank welcomes the “dialogue” regarding the “International Concoler Family Liman” adoption of “International Concoler Family Limit” for the EU level “.

“This is therefore added to compatible with national Pregnancy limitationIn addition, 75 families have actively implemented their international faces, “he said.

Sperm donating rules to know what about us

The United States does not have a legal limit on how much sperm donation of a person.

However, the American societies (ASRM) recommend the American society to be limited to 25,000 people within 800,000 people within each population of donors.

“Organizations, clinics and sperm banks should take enough notes to allow a restriction to be established Number of pregnancies For this, a donor is responsible for this, “Asrm said on the website.

“Limiting donor vials is an important part of the process.”

Creifal Cryobank, who claims that there is the biggest choice of sperm and egg donations in the country, follows the total number of family units around the world, which restricts the total number of family units up to 20-30.

“The Bank said the bank is an important part of the process that restricts vials.”

Baby girl's baby feet caught by mom

The US Federal Administration requires the physical examination of all sperm donors, completing a questionnaire, provides medical dates and provides medical dates and exposure to infectious diseases in a laboratory approved by the FDA. (Idle)

The US Federal Drug Administration (FDA) requires the physical examination of all sperm donors, completing a questionnaire, and provides medical dates and exposure to infectious diseases in a laboratory approved by the FDA.

In addition, the ASRM also suffered the psychological and genetic examination of donors and also recommends the test of the buyer and the buyer’s infectious diseases sexual intimate partnersaccording to the website.

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“Legal consultations and laws can be changed by the state,” the organization notes.

In California Crify Cryobank, donors should be tested for infectious diseases, pass a genetic examination, take psychological assessment and criminal origin and receive selection Zika virusAccording to the bank’s website.



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