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The blood of a US, who intentionally injected the intentional injecting with the poison of nearly needy, caused the “unparalleled” underneath.
The antibodies found in the blood of Tim Friede are shown to protect against fatal doses from wide species in animal tests.
Current therapies must be in line with special types of toxic snake that is bite.
However, Mr. Friede’s 18-year mission can be a significant step to find a universal antivan against all Snakeites who left many people who have killed and permanent disability.
In general, Mr. Friede is more than 200 vibrations of more than 200 vibrations, including more than 200 bite and the world’s most deadly snakes, including Mambas, Cobras, Cobras, Taipans and Kraits.
First, he wanted to establish immunity to protect yourself while the snakes work, document the operation on YouTube.
However, former truck mechanics, two COBRA bite in the fast sequence, when he left a coma when he left a coma, he said.
“I didn’t want to die. I didn’t want to lose a finger. I didn’t want to miss the work,” he said.
Mr. Friede’s motivation was to prepare better treatments for the rest of the world: “I just have to push and push and push and push and push and push and push and push and push and push and push for people 8,000 miles.”
Antienom is done with the entry of small doses of small doses of snake poisons such as horses. Their immune system fights poison by producing antibodies and is collected as therapy.
However, the toxins in a toxins in a toxic bite must match the poison and antenna because it changes from one kind to another.
There are even a wide range of same species – Antivoom from snakes in India becomes less effective Against the same types in Sri Lanka.
The researchers team began to search for an immune defense called an extensive neutralizing antibody. Instead of targeting a part of a toxin that makes a unique, Toxin target parts for all classes.
This came to Tim Friede, Cenivax Cendivax CEO Dr. Jacob Glanville.
“I was just like
“First call, I could have been awkward, but I would like to get my hands to your blood ‘.”
Mr Friede agreed and receives blood for more than poisoning to work, because the work has been confirmed.
Research is one of the two families of poisonous snakes, focused on elapids, coral snakes, mambas, cobras, taipans and kraits.
ElapIDs, primarily use neurotoxin who are damaged and deadly when the muscles are suspended to paralyze and breathe.
Researchers chose 19 elapids as among the world’s most deadly snakes in the world. Later, Mr. Friede’s blood began to sprinkle for protection.
Their work, Detailed in the magazine cellThe two class neurotoxin has set the target of two extensive harmless antibodies. They added a drug that targeted one-third to make Andenenom cocktail.
In practices in the mice, the cocktail was escaped from the fatal doses of 13 to 13 of the 19 types of poisonous snakes. There was partial protection from the remaining six.
According to Dr. Glanville, this “unparalleled” expansion, “It covers a group of a group of eats for the lack of current anvenom.”
The team then tries to cleanse the antibodies and sees a fourth component, which can be completely protected from the elapid snake poison.
Another snake class – Vipers – more confidence in hemotoxin who attacked more blood than neurotoxin. In general, there are several cytotoxins who are included in the cytoots, which are directly killed by the cells, have a few toxin, which includes a few toxins included.
“I think there will be something effective against each of these toxin classes in the next 10 or 15 years,” said Prof Peter Kwong, one of the researchers at the University of Columbia.
Hunt continues in the blood samples of Mr. Friede.
“Tim’s antibodies are really very unusual – he taught the immune system for very broad recognition,” said Prof Kwong.
Ultimate Hope is a injection for an antivom or elapid that can do everything and is to make a single injection for one of the leaps.
Snakebite Research and the head of the center of Snakebite Research and the head of the interventions in the Tropical Medical School, said that the defense width is “Of course” and this possible approach is “a strong piece of evidence”.
“There is no doubt that this work is progressing in an exciting direction.”
However, he said he was “much work” and Antivom needs a wide test before use in people.
But to reach this stage for Mr. Friede, “it feels good.”
“I’m doing something good for mankind, and this was very important to me. I am proud of him. It’s pretty cool.”